There are more than 375,000 people in the U.S. living with kidney, renal or pelvic cancer, according to the National Cancer Institute. Kidney cancer occurs roughly twice as often in males as in females, occurring most often in men between the ages of 40 and 60.

Renal cell carcinoma (RCC) is the most common type of kidney cancer that represents about 3 percent of all adult cancers. It is usually treated initially with surgery to remove the tumor. If caught in early stages, the chance that it will return is low. Unfortunately, renal cell carcinoma has few symptoms in early stages, so it can be undiagnosed or misdiagnosed until the tumor has grown fairly large.

Thirty percent of kidney cancer patients show signs of advanced RCC when diagnosed. Fifteen to 25 percent of patients have metastatic disease at the time of their diagnosis, meaning their cancer has spread to other areas of the body.

Clinical Trial of X-82 in combination with everolimus currently enrolling.